Kelly ain't got no tits left: In 2008, People reported that Applegate had been diagnosed with breast cancer. A representative stated, "Christina Applegate was diagnosed with an early stage of breast cancer. Detected early through a doctor-ordered MRI, the cancer was not life-threatening. Christina is following the recommended treatment of her doctors and will have a full recovery."[34] It was announced that she was cancer-free after a double mastectomy, although cancer had been found in only one breast.[35] She has an inherited genetic trait, a BRCA1[36] mutation, which can trigger breast and ovarian cancer. Her mother is also a breast cancer survivor. Applegate said when she first was diagnosed, "I was just shaking and then, also immediately, I had to go into 'take-care-of-business mode,' which included a change to a more healthy diet."[37] In August 2021, Applegate announced that she had been diagnosed with multiple sclerosis a few months prior.[38]