Nothing a neo black plague can't deal with That shit eradicated something like half the european pop circa medieval era https://en.wikipedia.org/wiki/Black_Death The Black Death is estimated to have killed 30% to 60% of Europe's population.[7] In total, the plague may have reduced the world population from an estimated 475 million to 350–375 million in the 14th century.[8] It took 200 years for the world population to recover to its previous level.[9] The plague recurred as outbreaks in Europe until the 19th century.