All flows around an object create Karman vortex streets in its wake. It doesn't matter what you do to limit the vortices. You can't stop them from happening, just like you can't stop resonance from happening. You can only dampen by destructive interference.
Birds use their flapping wings to shed vortices and ride the airflow they create, through the Karman wake.
https://www.youtube.com/watch?v=u8vyMHX9KNw
Here you see a starting vortex on the high pressure side of an airfoil, you see the vortex that is shed in effect entrains air over the low pressure side. In other words the vortex is sucking air over the low pressure side, accelerating it along the curvature of the wing.
Birds can keep their wings in sync with the movement of these "starting" vortices, fixed wing craft cannot.
Therefore fixed wing craft are more prone to perturbations from Karman wakes.
Even at extremely high Reynolds numbers we see Karman wakes
https://www.youtube.com/watch?v=LfDyIB6J8kM
And also at very low Re#
https://www.youtube.com/watch?v=k9FPxuhFlTo
The point of all of this is that if you want to reduce drag, or have more control over the wake vortices, then you have to play with geometry, length, leading edge thickness.
The stronger the trailing wake vortex, especially around a bluff body, the higher the drag, breaking up those trailing wake vortices can reduce drag. Preventing leading edge vortices can in some instances make trailing edge vortices more severe, in other cases less severe, depending on length and leading edge thickness.
https://youtu.be/ZCbZZ8OpP-g?t=61
(post is archived)