>VLA2001 consists of **inactivated whole virus particles of SARS-CoV-2 with high S-protein density, in combination with two adjuvants, alum and CpG 1018**. This adjuvant combination has consistently induced higher antibody levels in preclinical experiments than alum-only formulations and shown a shift of the immune response towards Th1 What’s the deal with their love for the S protein, usually viruses contain equal parts of the virus fragments. >The manufacturing process for VLA2001, which has already been upscaled to final industrial scale, **includes chemical inactivation to preserve the native structure of the S-protein. VLA2001 is expected to conform with standard cold chain requirements (2 degrees to 8 degrees Celsius)**. Why 2 degrees if it’s inactived? How many other vaccines need to be stored at 2 degrees. Pass. It’s probably inactived until room temperature