Uh, duh? The mRNA has the same RNA as SARS-CoV-2, creating the same spike protein as SARS-CoV-2 does when you're infected. The logic (as with vaccines in general) is that your body can generate a defense against this weak form, in preparation for the real thing.
The logic (as with vaccines in general) is that your body can generate a defense against this weak form, in preparation for the real thing.
Not as I understand it. In the case of mRNA vaccines the strategy is to saturate your body with the so called spike proteins so when the virus lands in there are fewer entry points for it. It's pretty much the same strategy as iodine pills against radioactive iodine; to saturate your hypophysis with normal iodine so it (hypophysis) can't absorb the radioactive one
TIL. If so, it would necessitate constant boosters. What a shitty approach, almost like it was engineered to not last.
Check this out https://pubmed.ncbi.nlm.nih.gov/34100279/ May-Jun 2021;
The COVID-19 pandemic necessitated the rapid production of vaccines aimed at the production of neutralizing antibodies against the COVID-19 spike protein required for the corona virus binding to target cells. The best well-known vaccines have utilized either mRNA or an adenovirus vector to direct human cells to produce the spike protein against which the body produces mostly neutralizing antibodies. However, recent reports have raised some skepticism as to the biologic actions of the spike protein and the types of antibodies produced. One paper reported that certain antibodies in the blood of infected patients appear to change the shape of the spike protein so as to make it more likely to bind to cells, while other papers showed that the spike protein by itself (without being part of the corona virus) can damage endothelial cells and disrupt the blood-brain barrier. These findings may be even more relevant to the pathogenesis of long-COVID syndrome that may affect as many as 50% of those infected with SARS-CoV-2. In COVID-19, a response to oxidative stress is required by increasing anti-oxidant enzymes. In this regard, it is known that polyphenols are natural anti-oxidants with multiple health effects. Hence, there are even more reasons to intervene with the use of anti-oxidant compounds, such as luteolin, in addition to available vaccines and anti-inflammatory drugs to prevent the harmful actions of the spike protein.
Alright, here is how it's supposed to work https://www.nebraskamed.com/COVID/how-mrna-vaccines-work
The mRNA vaccine goes into your arm. This mRNA instructs your own cells on how to build a part of a protein that the virus has. The needle will hurt like when receiving other vaccines
Your muscle cells take up this mRNA and read the instructions, building a spike protein that also is on the coronavirus (SARS-CoV-2) Some of the spike protein shows in part or in whole on the surface of these cells
Your immune system recognizes that the protein is different. It starts to produce antibodies as well as trains immune cells to recognize it in the future
When your body next sees SARS-CoV-2, some antibodies will be there to start protecting immediately, and immune cells will be primed to increase that protection
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So you got it mostly right I think. Unless this explanation is bogus of course.
>But here’s where the problem comes. In a virus, in a Coronavirus, that spike protein becomes part of the viral capsule. In other words, the cell wall around the virus, called the viral capsule. But it’s not in the virus. It’s in your cells. So it therefore becomes part of the cell wall of your vascular endothelium. Which means that these cells that line your blood vessels, which are supposed to be smooth so that blood flows smoothly, now have these little spikey bits sticking out. So it is absolutely inevitable that blood clots will form. Because your blood platelets circulate around in your blood vessels. And the purpose of blood platelets is to detect a damaged vessel and block that vessel to stop bleeding. So when the platelet comes through the capillary, it suddenly hits all these all these Covid spikes that are jutting into the inside of the vessel, it is absolutely inevitable that a blood clot will form to block that vessel. That’s how platelets work.
Well at first the pfizer leadership in charge of the vaccine said "Guys... This isn't going to work...". But they went for it anyways. For a reason I guess... In both cases.
Pfizer REJECTED the offer to develop Covid vaccine in January 2020 because executives thought the virus would be 'controlled' Pfizer executives initially thought that coronavirus would be rapidly contained They told BioNTech founders 'guys, this is not going to work' in January 2020 Dr Özlem Türeci and husband Dr Ugur Sahin believed it would only be a 'matter of time' before Pfizer changed its mind; a deal was announced a month later
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