Which should vary based on the risk it counters. If you have a 0.00001% chance of dying of some disease, it's going to be hard to justify any drug, no matter how safe.
Funny you should mention that number, roughly 1 in 10 million. Tetanus vaccines is one example that has been brought to my attention recently. Tetanus has 30 cases per year in the United States:
https://www.cdc.gov/tetanus/images/tetanus-chart-1947-2018.png
US population is about 300 million, so dividing 30 by that number gives us 0.00001% as the chance of being infected (not even dying). And the chance of ME getting infected is much less since I don't work on a farm or in construction where I might come in contact with rust.
And yet, when I went to my doctor for a checkup, what's the thing he asked? DiD yOu GeT yOuR tEtAnUs BoOsTeR???
Fucking clown world.
And to answer my next question, "how much is that tetanus number reduced by the tetanus vaccine?", .
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